Modification of Membrane Fluidity by Gravity

Erythrocyte Membrane Fluidity in

his study was conducted to investigate the values of the order parameter (S) and correlation time (τc) in electron spin resonance spectra for 5-DS(doxylstearic acid) and 16-DS (doxyl-stearic acid) in old normal controls and in patients with type 2 diabetes and stroke in order to assess any association between age-related disorders and membrane fluidity. Materials and Methods: We measured the me...

Desmosterol and Membrane Fluidity

Previous spin-label and electromyographic experiments with rats fed 20,25-diazacholesterol, an inhibitor of the biosynthet ic conversion of desmostero[ to cholesterol, demonstrated an increased e ry th rocy te membrane f luidi ty and myotonia, a prolonged muscle contraction upon stimulation. The current studies with rats showed normal erythrocyte f luidi ty in animals fed 20,25-diazacholesterol...

Control of membrane lipid fluidity by molecular thermosensors.

Impact of membrane fluidity on steric stabilization by lipopolymers.

In this work, the impact of lipid lateral mobility on the steric interaction between membranes containing poly(ethylene glycol) (PEG) functionalized lipids was investigated using the surface force apparatus. The force-distance profiles show the presence of electrostatic and steric repulsion that arise from the presence of negatively charged PEG functionalized lipids. Fluid-phase bilayers have h...

Modulation of canine myocardial sarcolemmal membrane fluidity by amphiphilic compounds.

Amphiphilic moieties such as lysophosphoglycerides and long-chain acyl carnitines accumulate in ischemic myocardium and potentially contribute to the sequelae of myocardial ischemia. To characterize alterations in membrane molecular dynamics produced by amphiphilic compounds, highly purified preparations of canine myocardial sarcolemma were spin-labeled with paramagnetic probes (5-, 12-, or 16-...